Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤여준 | - |
dc.date.accessioned | 2018-05-30T08:13:58Z | - |
dc.date.available | 2018-05-30T08:13:58Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.other | OAK-3345 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/243455 | - |
dc.description.abstract | Two new macrolides from the pikromycin biosynthetic pathway of Streptomyces venezuelae, neopikromycin (9) and novapikromycin (10), were identified and structurally characterized through mass spectrometry and NMR spectroscopy. The established structures showed that 9 and 10 have hydroxyl groups at C-14 (9) and at both C-12 and C-14 (10), on the basis of a comparison with narbomycin (7). The purified PikC cytochrome P450 monooxygenase catalyzes the in vitro hydroxylation of 7 and pikromycin (8) to yield 9 and 10, respectively, thus expanding the substrate- and regio-flexibility of this enzyme. © 2006 American Chemical Society and American Society of Pharmacognosy. | - |
dc.language | English | - |
dc.title | Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae | - |
dc.type | Article | - |
dc.relation.issue | 5 | - |
dc.relation.volume | 69 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 847 | - |
dc.relation.lastpage | 849 | - |
dc.relation.journaltitle | Journal of Natural Products | - |
dc.identifier.doi | 10.1021/np060026p | - |
dc.identifier.wosid | WOS:000237816700029 | - |
dc.identifier.scopusid | 2-s2.0-33745777367 | - |
dc.author.google | Lee S.K. | - |
dc.author.google | Park J.W. | - |
dc.author.google | Kim J.W. | - |
dc.author.google | Jung W.S. | - |
dc.author.google | Park S.R. | - |
dc.author.google | Choi C.Y. | - |
dc.author.google | Kim E.S. | - |
dc.author.google | Kim B.S. | - |
dc.author.google | Ahn J.S. | - |
dc.author.google | Sherman D.H. | - |
dc.author.google | Yoon Y.J. | - |
dc.contributor.scopusid | 윤여준(7402126465) | - |
dc.date.modifydate | 20210708161345 | - |