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Synthesis of halogenated 9-(dihydroxycyclopent-4′-enyl) adenines and their inhibitory activities against S-Adenosylhomocysteine hydrolase

Title: Synthesis of halogenated 9-(dihydroxycyclopent-4′-enyl) adenines and their inhibitory activities against S-Adenosylhomocysteine hydrolase

Authors: Jeong L.S.; Park J.G.; Choi W.J.; Moon H.R.; Lee K.M.; Kim H.O.; Kim H.-D.; Chun M.W.; Park H.-Y.; Kim K.; Sheen Y.Y.

Ewha Authors: 정낙신

SCOPUS Author ID: 정낙신

Issue Date: 2003

Journal Title: Nucleosides, Nucleotides and Nucleic Acids

ISSN: 1525-7770

Citation: Nucleosides, Nucleotides and Nucleic Acids vol. 22, no. 5-8, pp. 919 - 921

Indexed: SCIE; SCOPUS

Document Type: Conference Paper

Abstract: Novel halovinyl analogues of neplanocin A without 4′-hydroxymethyl group were easily synthesized starting from D-ribose via cyclopentenone 5 as a key intermediate and their inhibitory activity against SAH hydrolase was assayed.

DOI: 10.1081/NCN-120022686

Appears in Collections:: 약학대학 > 약학과 > Journal papers

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