Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상국 | - |
dc.date.accessioned | 2018-05-02T08:15:44Z | - |
dc.date.available | 2018-05-02T08:15:44Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.other | OAK-2141 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/242788 | - |
dc.description.abstract | The inhibitory effects of a series of styrylheterocycles on the production of cyclooxygenase-2-mediated prostaglandin E2 (PGE2) were evaluated in lipopolysaccharide-stimulated RAW264.7 murine macrophages. A new series of potential inhibitors, including 3-[2-(4-methoxy-phenyl)-vinyl]- thiophene, have been identified, thus providing novel chemical leads for the further development of potential inhibitors in this capacity. The suppression of COX-2 mRNA expression by the active styrylheterocycles, in part, was involved in the inhibitory activity against the overproduction of PGE2. © 2004 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.title | Styrylheterocycles as a novel class inhibitor of cyclooxygenase-2-mediated prostaglandin E2 production | - |
dc.type | Article | - |
dc.relation.issue | 9 | - |
dc.relation.volume | 14 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 2105 | - |
dc.relation.lastpage | 2108 | - |
dc.relation.journaltitle | Bioorganic and Medicinal Chemistry Letters | - |
dc.identifier.doi | 10.1016/j.bmcl.2004.02.038 | - |
dc.identifier.wosid | WOS:000221160200017 | - |
dc.identifier.scopusid | 2-s2.0-1842791405 | - |
dc.author.google | Lee S.K. | - |
dc.author.google | Park E.-J. | - |
dc.author.google | Lee E. | - |
dc.author.google | Min H.-Y. | - |
dc.author.google | Kim E.-Y. | - |
dc.author.google | Lee T. | - |
dc.author.google | Kim S. | - |
dc.contributor.scopusid | 이상국(36067620500) | - |
dc.date.modifydate | 20211210153309 | - |