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Novel platinum complexes having chirality and free tertiary amine groups for multiple interactions with DNA

Title
Novel platinum complexes having chirality and free tertiary amine groups for multiple interactions with DNA
Authors
Seo M.S.Soo Sohn Y.Yang B.-S.Nam W.Mook Kim K.
Ewha Authors
남원우손연수김관묵서미숙
SCOPUS Author ID
남원우scopus; 손연수scopus; 김관묵scopus
Issue Date
2004
Journal Title
Inorganic Chemistry Communications
ISSN
1387-7003JCR Link
Citation
Inorganic Chemistry Communications vol. 7, no. 11, pp. 1178 - 1180
Indexed
SCI; SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Chiral ethylenediamine ligands with free tertiary amine groups and their platinum complexes are synthesized. The platinum complexes have both chirality and additional DNA interacting groups. The hydrogen bonding interactions in the crystal structure lead to the dimerization of two platinum complexes having pocket-like cavity with chiral shapes. Chiral ethylenediamine ligands with free tertiary amine groups and their platinum complexes are synthesized. The platinum complexes have both chirality and additional DNA interacting groups. The hydrogen bonding interactions between chlorides and two tertiary amine groups in the crystal structure lead to the dimerization of two platinum complexes having pocket-like cavity with chiral shapes. © 2004 Elsevier B.V. All rights reserved.
DOI
10.1016/j.inoche.2004.09.007
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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