Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박진병 | * |
dc.contributor.author | 송지원 | * |
dc.date.accessioned | 2018-04-25T08:13:32Z | - |
dc.date.available | 2018-04-25T08:13:32Z | - |
dc.date.issued | 2018 | * |
dc.identifier.issn | 1615-4150 | * |
dc.identifier.issn | 1615-4169 | * |
dc.identifier.other | OAK-22056 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/242529 | - |
dc.description.abstract | Regiospecific oxyfunctionalization of renewable long chain fatty acids into industrially relevant C9 carboxylic acids has been investigated. One example was biocatalytic transformation of 10,12-dihydroxyoctadecanoic acid, which was produced from ricinoleic acid ((9Z,12R)-12-hydroxyoctadec-9-enoic acid) by a fatty acid double bond hydratase, into (R)-3-hydroxynonanoic acid, 9-hydroxynonanoic acid, and 1,9-nonanedioic acid with a high conversion yield of ca. 70%. The biotransformation was driven by enzyme/whole-cell biocatalysts, consisting of the esterase of Pseudomonas fluorescens and the recombinant Escherichia coli expressing the secondary alcohol dehydrogenase of Micrococcus luteus, the Baeyer-Villiger monooxygenase of Pseudomonas putida KT2440 and the primary alcohol/aldehyde dehydrogenases of Acinetobacter sp. NCIMB9871. The high conversion yields and the high product formation rates over 20 U/g dry cells with insoluble reactants indicated that various (poly-hydroxy) fatty acids could be converted into multi-functional products via the simultaneous enzyme/whole-cell biotransformations. This study will contribute to the enzyme-based functionalization of hydrophobic substances. | * |
dc.language | English | * |
dc.publisher | WILEY-V C H VERLAG GMBH | * |
dc.subject | Enzyme catalysis | * |
dc.subject | Oxygenation | * |
dc.subject | Carboxylic acids | * |
dc.subject | Biotransformation | * |
dc.subject | Fatty acids | * |
dc.title | Simultaneous Enzyme/Whole-Cell Biotransformation of C18 Ricinoleic Acid into (R)-3-Hydroxynonanoic Acid, 9-Hydroxynonanoic Acid, and 1,9-Nonanedioic Acid | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 360 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 696 | * |
dc.relation.lastpage | 703 | * |
dc.relation.journaltitle | ADVANCED SYNTHESIS & CATALYSIS | * |
dc.identifier.doi | 10.1002/adsc.201701029 | * |
dc.identifier.wosid | WOS:000425114600014 | * |
dc.identifier.scopusid | 2-s2.0-85038076147 | * |
dc.author.google | Cha, Hee-Jeong | * |
dc.author.google | Seo, Eun-Ji | * |
dc.author.google | Song, Ji-Won | * |
dc.author.google | Jo, Hye-Jin | * |
dc.author.google | Kumar, Akula Ravi | * |
dc.author.google | Park, Jin-Byung | * |
dc.contributor.scopusid | 박진병(15036390700) | * |
dc.contributor.scopusid | 송지원(56118399000) | * |
dc.date.modifydate | 20240322114808 | * |