View : 61 Download: 13

Versatile Chemical Derivatizations to Design Glycol Chitosan-Based Drug Carriers

Title
Versatile Chemical Derivatizations to Design Glycol Chitosan-Based Drug Carriers
Authors
Kim, Sung EunKim, Hak-JunRhee, Jin-KyuPark, Kyeongsoon
Ewha Authors
이진규
SCOPUS Author ID
이진규scopus
Issue Date
2017
Journal Title
MOLECULES
ISSN
1420-3049JCR Link
Citation
vol. 22, no. 10
Keywords
glycol chitosanchemical derivatizationsnanoparticlesdrug carriersdisease therapy
Publisher
MDPI AG
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Glycol chitosan (GC) and its derivatives have been extensively investigated as safe and effective drug delivery carriers because of their unique physiochemical and biological properties. The reactive functional groups such as the amine and hydroxyl groups on the GC backbone allow for easy chemical modification with various chemical compounds (e.g., hydrophobic molecules, crosslinkers, and acid-sensitive and labile molecules), and the versatility in chemical modifications enables production of a wide range of GC-based drug carriers. This review summarizes the versatile chemical modification methods that can be used to design GC-based drug carriers and describes their recent applications in disease therapy.
DOI
10.3390/molecules22101662
Appears in Collections:
엘텍공과대학 > 식품공학전공 > Journal papers
Files in This Item:
Versatile chemical derivatizations.pdf(1.62 MB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE