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Portable cyanobacteria detection fluorometer with current-conveyor transimpedance amplifiers

Title
Portable cyanobacteria detection fluorometer with current-conveyor transimpedance amplifiers
Authors
He Y.Park S.M.
Ewha Authors
박성민
SCOPUS Author ID
박성민scopus
Issue Date
2017
Journal Title
Journal of Semiconductor Technology and Science
ISSN
1598-1657JCR Link
Citation
vol. 17, no. 6, pp. 886 - 892
Keywords
Current-conveyorCyanobacteriaFluorometerQuantum dotsTransimpedance amplifier
Publisher
Institute of Electronics Engineers of Korea
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
A portable fluorometer has been developed for cyanobacteria detection by exploiting commercially available low-cost photodiodes. Particularly, the front-end detection circuit was integrated on-chip by using a 0.11-mm CMOS process to realize the high transimpedance gain of 99.7 dBΩ with low current consumption of 1.4 mA from a single 1.5-V supply, hence providing a low-power solution with small form-factor in the applications of portable cyanobacteria detection. For measuring fluorescence intensity of cyanobacteria, two quantum dots of QD565 and QD655 were employed into a NanoGene assay for mcyD gene(synthetase of toxic microcystin) detection of Microcystis aeruginosa, resulting in two different readout voltages. Various operational parameters (e.g. distance, angle between laser emission and vial sample, etc) were investigated for the proposed fluorometer. Measurements demonstrated that the mcyD gene hybridized with QD565 and QD655 was quantitatively detected, i.e. the normalized output voltage (QD655/QD565) was linearly proportional to the mcyD gene copy numbers (y = 0.25 log x – 0.25). Besides, the wireless transfer of the quantitative data was performed via Bluetooth. © 2017, Institute of Electronics Engineers of Korea. All rights reserved.
DOI
10.5573/JSTS.2017.17.6.886
Appears in Collections:
엘텍공과대학 > 전자공학과 > Journal papers
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