Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 정낙신 | - |
dc.date.accessioned | 2017-11-22T06:30:04Z | - |
dc.date.available | 2017-11-22T06:30:04Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0956-3202 | - |
dc.identifier.other | OAK-18076 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/239205 | - |
dc.description.abstract | Compared with 4′-oxonucleosides, there have been far fewer systematic structure-activity relationship studies on carbocyclic nucleosides as antiviral and antitumour agents. This is mainly because of the synthetic problems in preparing the carbasugars. However, the recent discovery of the ring-closing metathesis (RCM) (a powerful tool for the preparation of 5-membered carbasugar via C-C bond formation) has made it possible to synthesize the key carbasugars to a preparative scale. This review summarizes the asymmetric syntheses of carbasugars and carbocyclic nucleosides, using an RCM reaction as a key step. Furthermore, the review includes valuable information for designing and synthesizing novel carbocyclic nucleosides. | - |
dc.language | English | - |
dc.title | Recent advances in the synthesis of the carbocyclic nucleosides as potential antiviral agents | - |
dc.type | Review | - |
dc.relation.issue | 5 | - |
dc.relation.volume | 15 | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 235 | - |
dc.relation.lastpage | 250 | - |
dc.relation.journaltitle | Antiviral Chemistry and Chemotherapy | - |
dc.identifier.scopusid | 2-s2.0-7544241609 | - |
dc.author.google | Jeong L.S. | - |
dc.author.google | Lee J.A. | - |
dc.contributor.scopusid | 정낙신(16028528200) | - |
dc.date.modifydate | 20211210153610 | - |