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Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities

Title
Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities
Authors
Kil Y.-S.Pham S.T.Seo E.K.Jafari M.
Ewha Authors
서은경
SCOPUS Author ID
서은경scopus
Issue Date
2017
Journal Title
Archives of Pharmacal Research
ISSN
0253-6269JCR Link
Citation
vol. 40, no. 6, pp. 655 - 675
Keywords
Angelica keiskeiBiological activityChemical constituentUmbelliferae
Publisher
Pharmaceutical Society of Korea
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food. Various flavonoids, coumarins, phenolics, acetylenes, sesquiterpene, diterpene, and triterpenes were identified as the constituents of A. keiskei. The crude extracts and pure constituents were proven to inhibit tumor growth and ameliorate inflammation, obesity, diabetics, hypertension, and ulcer. The extract also showed anti-thrombotic, anti-oxidative, anti-hyperlipidemic, anti-viral, and anti-bacterial activities. This valuable herb needs to be further studied and developed not only to treat these human diseases but also to improve human health. Currently A. keiskei is commercialized as a health food and additives in health drinks. This article presents a comprehensive review of A. keiskei and its potential place in the improvement of human health. © 2017, The Pharmaceutical Society of Korea.
DOI
10.1007/s12272-017-0892-3
Appears in Collections:
약학대학 > 약학과 > Journal papers
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