Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 차선신 | * |
dc.date.accessioned | 2017-05-30T01:05:21Z | - |
dc.date.available | 2017-05-30T01:05:21Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0066-4804 | * |
dc.identifier.issn | 1098-6596 | * |
dc.identifier.other | OAK-20575 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/235204 | - |
dc.description.abstract | Nucleotides were effective in inhibiting the class C beta-lactamase CMY-10. IMP was the most potent competitive inhibitor, with a K-i value of 16.2 mu M. The crystal structure of CMY-10 complexed with GMP or IMP revealed that nucleotides fit into the R2 subsite of the active site with a unique vertical binding mode where the phosphate group at one terminus is deeply bound in the subsite and the base at the other terminus faces the solvent. | * |
dc.language | English | * |
dc.publisher | AMER SOC MICROBIOLOGY | * |
dc.subject | GMP | * |
dc.subject | IMP | * |
dc.subject | beta-lactamases | * |
dc.subject | competitive inhibitor | * |
dc.title | GMP and IMP Are Competitive Inhibitors of CMY-10, an Extended-Spectrum Class C beta-Lactamase | * |
dc.type | Article | * |
dc.relation.issue | 5 | * |
dc.relation.volume | 61 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | * |
dc.identifier.doi | 10.1128/AAC.00098-17 | * |
dc.identifier.wosid | WOS:000403532100010 | * |
dc.identifier.scopusid | 2-s2.0-85018186854 | * |
dc.author.google | Na, Jung-Hyun | * |
dc.author.google | An, Young Jun | * |
dc.author.google | Cha, Sun-Shin | * |
dc.contributor.scopusid | 차선신(7201864593) | * |
dc.date.modifydate | 20240429134916 | * |