View : 234 Download: 0

Anti-diabetic Potential of Silver Nanoparticles Synthesized with Argyreia nervosa Leaf Extract High Synergistic Antibacterial Activity with Standard Antibiotics Against Foodborne Bacteria

Title
Anti-diabetic Potential of Silver Nanoparticles Synthesized with Argyreia nervosa Leaf Extract High Synergistic Antibacterial Activity with Standard Antibiotics Against Foodborne Bacteria
Authors
Saratale, Ganesh DattatrayaSaratale, Rijuta GaneshBenelli, GiovanniKumar, GopalakrishnanPugazhendhi, ArivalaganKim, Dong-SuShin, Han-Seung
Ewha Authors
김동수
SCOPUS Author ID
김동수scopus
Issue Date
2017
Journal Title
JOURNAL OF CLUSTER SCIENCE
ISSN
1040-7278JCR Link1572-8862JCR Link
Citation
vol. 28, no. 3, pp. 1709 - 1727
Keywords
Antidiabetic drugsArgyreia nervosa leaves extractSilver nanoparticlesABTS free radical scavenging activityMinimum inhibitory concentrationStaphylococcus aureus
Publisher
SPRINGER/PLENUM PUBLISHERS
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
The current investigation highlighted a novel cost-effective green synthesis of silver nanoparticles (AgNPs) using Argyreia nervosa leaves extract (ANE) as a potential reducing and capping agent. Surface plasmon resonance confirmed the formation of AgNPs with maximum absorbance at lambda (max) = 435 nm. FTIR revealed the involvement of biological macromolecules of ANE in the synthesis and stabilization of AgNPs. HRTEM images showed that the size of the spherical AgNPs ranged between 5 and 40 nm with average particle size of about 15 nm. The ANE-AgNPs showed inhibition activity against carbohydrate digestive enzymes alpha-amylase and alpha-glucosidase, with EC50 of 55.5 and 51.7 A mu g/mL, respectively, indicating its antidiabetic potential. The in vitro antioxidant activity of ANE-AgNPs was evaluated in terms of ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) and DPPH (1,1-diphenyl-2-picrylhydrazyl) free radicals scavenging assays with IC50 value of 44.3 and 55.9 A mu g/mL, respectively. The AgNPs displayed strong antibacterial activity against foodborne bacteria with zone of inhibition 16.0 and 12.5 mm for Escherichia coli and Staphylococcus aureus, respectively, and also exhibited strong synergistic antibacterial activity together with standard antibiotics. The biological activity in terms of antioxidant, antidiabetic and antibacterial potential could be useful in various bio-applications such as cosmetics, food, and biomedical industry.
DOI
10.1007/s10876-017-1179-z
Appears in Collections:
엘텍공과대학 > 환경공학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE