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Synthesis and antifungal activity of 6-arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones
- Title
- Synthesis and antifungal activity of 6-arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones
- Authors
- Ryu C.-K.; Park R.-E.; Ma M.-Y.; Nho J.-H.
- Ewha Authors
- 유충규
- SCOPUS Author ID
- 유충규
- Issue Date
- 2007
- Journal Title
- Bioorganic and Medicinal Chemistry Letters
- ISSN
- 0960-894X
- Citation
- Bioorganic and Medicinal Chemistry Letters vol. 17, no. 9, pp. 2577 - 2580
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- 6-Arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among those tested, many compounds showed good antifungal activity. The results suggest that phthalazine-5,8-diones would be potent antifungal agents. © 2007 Elsevier Ltd. All rights reserved.
- DOI
- 10.1016/j.bmcl.2007.02.003
- Appears in Collections:
- 약학대학 > 약학과 > Journal papers
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