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Synthesis and antifungal activity of 6-arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones

Title
Synthesis and antifungal activity of 6-arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones
Authors
Ryu C.-K.Park R.-E.Ma M.-Y.Nho J.-H.
Ewha Authors
유충규
SCOPUS Author ID
유충규scopus
Issue Date
2007
Journal Title
Bioorganic and Medicinal Chemistry Letters
ISSN
0960-894XJCR Link
Citation
vol. 17, no. 9, pp. 2577 - 2580
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
6-Arylamino-phthalazine-5,8-diones and 6,7-bis(arylthio)-phthalazine-5,8-diones were synthesized and tested for in vitro antifungal activity against two pathogenic strains of fungi. Among those tested, many compounds showed good antifungal activity. The results suggest that phthalazine-5,8-diones would be potent antifungal agents. © 2007 Elsevier Ltd. All rights reserved.
DOI
10.1016/j.bmcl.2007.02.003
Appears in Collections:
약학대학 > 약학과 > Journal papers
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