Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 곽혜선 | * |
dc.date.accessioned | 2017-02-15T08:02:57Z | - |
dc.date.available | 2017-02-15T08:02:57Z | - |
dc.date.issued | 2007 | * |
dc.identifier.issn | 1071-7544 | * |
dc.identifier.other | OAK-3812 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/234237 | - |
dc.description.abstract | The effects of pressure-sensitive adhesives and vehicles on the in vitro permeation of ketorolac and in vivo pharmacokinetics were studied. Duro-Tak 87-2196® showed the highest in vitro permeation profiles, and propylene glycol monolaurate-diethylene glycol monoethyl ether (DGME) (60:40, v/v) and propylene glycol monocaprylate-DGME (60:40, v/v) revealed the most favorable in vitro and in vivo results. The decreased Cmax and prolonged Tmax and half-life were obtained with the ketorolac transdermal systems compared with oral administration, indicating that the ketorolac transdermal systems may have a prolonged effect with reduced toxic event. There was an excellent relationship found between in vitro permeation flux and in vivo AUC0-∞. Copyright © Informa Healthcare. | * |
dc.language | English | * |
dc.title | Formulation and evaluation of ketorolac transdermal systems | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 14 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 69 | * |
dc.relation.lastpage | 74 | * |
dc.relation.journaltitle | Drug Delivery | * |
dc.identifier.doi | 10.1080/10717540600640336 | * |
dc.identifier.wosid | WOS:000243882900002 | * |
dc.identifier.scopusid | 2-s2.0-33847029891 | * |
dc.author.google | Choi J.S. | * |
dc.author.google | Cho Y.A. | * |
dc.author.google | Chun I.K. | * |
dc.author.google | Jung S.Y. | * |
dc.author.google | Gwak H.S. | * |
dc.date.modifydate | 20240422115307 | * |