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Transmembrane domain-dependent functional oligomerization of syndecans

Title
Transmembrane domain-dependent functional oligomerization of syndecans
Authors
Jae Y.Y.Han I.Oh E.-S.
Ewha Authors
오억수
SCOPUS Author ID
오억수scopus
Issue Date
2006
Journal Title
TheScientificWorldJournal
ISSN
1537-744XJCR Link
Citation
vol. 6, pp. 457 - 459
Indexed
SCOPUS WOS scopus
Abstract
Cell surface adhesion receptors of the syndecan family initiate intracellular events through clustering of receptors. This crucial clustering occurs through receptor dimerization or oligomerization, which is mediated by receptor transmembrane domains. However, the exact role of the transmembrane domain during receptor activation is not fully understood. Researchers have not yet determined whether the transmembrane domain functions solely in the physical aspects of receptor clustering, or whether the domain has additional functional roles. Here we review recent advances in understanding the functionality of transmembrane domain-dependent oligomerization of syndecan cell adhesion receptor. ©2006 with author. Published by TheScientificWorld, Ltd.
DOI
10.1100/tsw.2006.92
Appears in Collections:
자연과학대학 > 생명과학전공 > Journal papers
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