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Stereoselective synthesis of 2′-C-methyl-cyclopropyl-fused carbanucleosides as potential anti-HCV agents

Title
Stereoselective synthesis of 2′-C-methyl-cyclopropyl-fused carbanucleosides as potential anti-HCV agents
Authors
Lee J.A.Hea O.K.Tosh D.K.Hyung R.M.Kim S.Lak S.J.
Ewha Authors
정낙신
Issue Date
2006
Journal Title
Organic Letters
ISSN
1523-7060JCR Link
Citation
vol. 8, no. 22, pp. 5081 - 5083
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
(Chemical Equation Presented) Stereoselective synthesis of 2′-C-methyl-cyclopropyl-fused carbanucleosides was accomplished via stereoselective cyclopropanation, regioselective cleavage of the isopropylidene group, stereoselective Grignard reaction, and cyclic sulfate chemistry. © 2006 American Chemical Society.
DOI
10.1021/ol061959f
Appears in Collections:
약학대학 > 약학과 > Journal papers
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