Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 유충규 | - |
dc.date.accessioned | 2017-02-15T08:02:27Z | - |
dc.date.available | 2017-02-15T08:02:27Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0968-0896 | - |
dc.identifier.other | OAK-3506 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/234090 | - |
dc.description.abstract | 5-Arylamino-1H-benzo[d]imidazole-4,7-diones were synthesized and tested for their inhibitory activities on the proliferation of human umbilical vein endothelial cells (HUVECs) and the smooth muscle cells (SMCs). Among them, several 1H-benzo[d]imidazole-4,7-diones exhibited the selective antiproliferative activity on the HUVECs. Further mechanistic study revealed that the inhibitory effect of one representative 1H-benzo[d]imidazole-4,7-dione 2b on HUVEC proliferation was mediated by the activation of p38 signaling pathway in the HUVECs. © 2006. | - |
dc.language | English | - |
dc.title | Synthesis and biological evaluation of 5-arylamino-1H-benzo[d]imidazole-4,7-diones as inhibitor of endothelial cell proliferation | - |
dc.type | Article | - |
dc.relation.issue | 17 | - |
dc.relation.volume | 14 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 5795 | - |
dc.relation.lastpage | 5801 | - |
dc.relation.journaltitle | Bioorganic and Medicinal Chemistry | - |
dc.identifier.doi | 10.1016/j.bmc.2006.05.059 | - |
dc.identifier.wosid | WOS:000239947500002 | - |
dc.identifier.scopusid | 2-s2.0-33746075919 | - |
dc.author.google | Chung K.-H. | - |
dc.author.google | Hong S.-Y. | - |
dc.author.google | You H.-J. | - |
dc.author.google | Park R.-E. | - |
dc.author.google | Ryu C.-K. | - |
dc.contributor.scopusid | 유충규(15846918400) | - |
dc.date.modifydate | 20170901081001 | - |