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Mixed micelle-template route to mesoporous silica

Title
Mixed micelle-template route to mesoporous silica
Authors
Son Y.-H.Park M.Kim S.T.Choy J.-H.
Ewha Authors
최진호김상태
SCOPUS Author ID
최진호scopus
Issue Date
2007
Journal Title
Journal of Nanoscience and Nanotechnology
ISSN
1533-4880JCR Link
Citation
vol. 7, no. 11, pp. 3819 - 3822
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Mesoporous silica materials were prepared through a novel mixed micelle-template method which was employed by alkyl polyethylene oxide (C 16E 20) and C 2-ceramide. X-ray diffraction patterns clearly showed the formation of mesoporous silica by contribution of mixed micelle-template up to 3/1 weight ratio (C 16E 20/C 2-ceramide). TEM and N 2 adsorption isotherms analyses indicated that the mesoporous structure was maintained even after encased C 2-ceramides. However, when the weight ratio of C 16E 20/C 2-ceramide exceeds 2/2, less ordered and irregular pore structure was observed. According to the in-vitro experiment on cancer cells such as MCF-7, HOS, and HepG2, the simultaneously encapsulated C 2-ceramide shows apoptosis. Therefore, the present results could provide a new method for mesoporous material as drug delivery system. Copyright © 2007 American Scientific Publishers All rights reserved.
DOI
10.1166/jnn.2007.037
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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