Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이상기 | * |
dc.date.accessioned | 2017-01-14T02:01:48Z | - |
dc.date.available | 2017-01-14T02:01:48Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 1523-7060 | * |
dc.identifier.other | OAK-19963 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/233881 | - |
dc.description.abstract | A novel, one-pot route for the synthesis of nonaromatic ring-fused 1,4-oxazepines and 1,4-oxazines has been developed. The reaction features a sequential rhodium(II)-catalyzed reaction of N-sulfonyl-1,2,3-triazoles with glycidols, followed by a regioselective Lewis acid Mg(OtBu)2-catalyzed intramolecular ring-opening reaction. It has been found that the regioselectivity in the epoxide ring-opening was largely determined by the substituents on the glycidols. Thus, substituted glycidols (R2 ≠ H) afforded seven-membered oxazepine derivatives selectively, while unsubstituted glycidols (R2 = H) afforded six-membered oxazine derivatives. Plausible reaction pathways are elucidated and supported by experiments with several glycidols bearing different substituents around the epoxide functionality. © 2016 American Chemical Society. | * |
dc.language | English | * |
dc.publisher | American Chemical Society | * |
dc.title | Rh(II)/Mg(OtBu)2-Catalyzed Tandem One-Pot Synthesis of 1,4-Oxazepines and 1,4-Oxazines from N-Sulfonyl-1,2,3-triazoles and Glycidols | * |
dc.type | Article | * |
dc.relation.issue | 24 | * |
dc.relation.volume | 18 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 6432 | * |
dc.relation.lastpage | 6435 | * |
dc.relation.journaltitle | Organic Letters | * |
dc.identifier.doi | 10.1021/acs.orglett.6b03328 | * |
dc.identifier.wosid | WOS:000390180300055 | * |
dc.identifier.scopusid | 2-s2.0-85006265990 | * |
dc.author.google | Ko Y.O. | * |
dc.author.google | Jeon H.J. | * |
dc.author.google | Jung D.J. | * |
dc.author.google | Kim U.B. | * |
dc.author.google | Lee S.-G. | * |
dc.contributor.scopusid | 이상기(15082786300) | * |
dc.date.modifydate | 20240123104103 | * |