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DSpace at EWHA약학대학 약학과 Journal papers

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Synthesis and biological evaluation of halo-neplanocin A as novel mechanism-based inhibitors of S-Adenosylhomocysteine hydrolase

Title: Synthesis and biological evaluation of halo-neplanocin A as novel mechanism-based inhibitors of S-Adenosylhomocysteine hydrolase

Authors: Jeong L.S.; Moon H.R.; Park J.G.; Shin D.H.; Choi W.J.; Lee K.M.; Kim H.O.; Chun M.W.; Kim H.-D.; Kim J.H.

Ewha Authors: 정낙신

SCOPUS Author ID: 정낙신

Issue Date: 2003

Journal Title: Nucleosides, Nucleotides and Nucleic Acids

ISSN: 1525-7770

Citation: Nucleosides, Nucleotides and Nucleic Acids vol. 22, no. 5-8, pp. 589 - 592

Indexed: SCIE; SCOPUS

Document Type: Conference Paper

Abstract: Halogenated analogues of neplanocin A were synthesized from the key intermediate 1, among which fluoro-neplanocin A was found to be novel mechanism-based irreversible inhibitor of S-Adenosylhomocysteine hydrolase.

DOI: 10.1081/NCN-120021961

Appears in Collections:: 약학대학 > 약학과 > Journal papers

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