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dc.contributor.author정낙신-
dc.contributor.author김대기-
dc.date.accessioned2017-01-05T02:01:08Z-
dc.date.available2017-01-05T02:01:08Z-
dc.date.issued2004-
dc.identifier.issn0968-0896-
dc.identifier.otherOAK-1845-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/233639-
dc.description.abstractThe present work describes the asymmetric synthesis of D- and L-apio-2′,3′-dideoxynucleoside analogues, 4 and 5 with 2′-hydroxyl group via a common intermediate 9, starting from D-galactose. Stereoselective dihydroxylation and deoxygenation through radical inversion were successfully employed to synthesize the key intermediate 12 with D-apio structure, while stereoselecetive hydroboration-oxidation was used for the synthesis of another key intermediate 18 with L-apio structure. © 2003 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.titleSynthesis of D- and L-apio nucleoside analogues with 2′-hydroxyl group as potential anti-HIV agents-
dc.typeArticle-
dc.relation.issue5-
dc.relation.volume12-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage1101-
dc.relation.lastpage1109-
dc.relation.journaltitleBioorganic and Medicinal Chemistry-
dc.identifier.doi10.1016/j.bmc.2003.12.002-
dc.identifier.wosidWOS:000189314700028-
dc.identifier.scopusid2-s2.0-1342321885-
dc.author.googleJin D.Z.-
dc.author.googleKwon S.H.-
dc.author.googleMoon H.R.-
dc.author.googleGunaga P.-
dc.author.googleKim H.O.-
dc.author.googleKim D.-K.-
dc.author.googleChun M.W.-
dc.author.googleJeong L.S.-
dc.contributor.scopusid김대기(35083694200)-
dc.date.modifydate20170518153159-
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약학대학 > 약학과 > Journal papers
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