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Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes

Title
Effect of chitin/silk fibroin nanofibrous bicomponent structures on interaction with human epidermal keratinocytes
Authors
Yoo C.R.Yeo I.-S.Park K.E.Park J.H.Lee S.J.Park W.H.Min B.-M.
Ewha Authors
이승진
SCOPUS Author ID
이승진scopus
Issue Date
2008
Journal Title
International Journal of Biological Macromolecules
ISSN
0141-8130JCR Link
Citation
vol. 42, no. 4, pp. 324 - 334
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
To fabricate a biomimetic nanostructured bicomponent scaffolds, two types of chitin/silk fibroin (SF) nanofibrous scaffolds (blend scaffolds and hybrid scaffolds) were prepared by electrospinning or simultaneous electrospinning of chitin/SF solutions. The chitin/SF bicomponent scaffolds were after-treated with water vapor, and their nanofibrous structures were almost maintained. From the cytocompatibility and cell behavior on the chitin/SF blend or hybrid nanofibrous scaffolds, the hybrid matrix with 25% chitin and 75% SF as well as the chitin/SF blend nanofibers could be a potential candidate for tissue engineering scaffolds. © 2008 Elsevier B.V. All rights reserved.
DOI
10.1016/j.ijbiomac.2007.12.004
Appears in Collections:
약학대학 > 약학과 > Journal papers
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