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Au-droped magnetic silica nanotube for binding of cysteine-containing proteins
- Title
- Au-droped magnetic silica nanotube for binding of cysteine-containing proteins
- Authors
- Bae D.R.; Lee S.J.; Han S.W.; Lim J.M.; Kang D.; Jung J.H.
- Ewha Authors
- 강동민
- SCOPUS Author ID
- 강동민
- Issue Date
- 2008
- Journal Title
- Chemistry of Materials
- ISSN
- 0897-4756
- Citation
- Chemistry of Materials vol. 20, no. 12, pp. 3809 - 3813
- Indexed
- SCI; SCIE; SCOPUS
- Document Type
- Article
- Abstract
- The Au-doped magnetic silica nanotube (Au-MSNT) was fabricated by sol-gel transcription and its binding ability for proteins was carried out by TEM, FIF-IR, and confocal microscope. The nickel nanoparticles with 3.5 ± 1.0 nm are homogeneously deposited on the inner side of a silica nanotube (SNT) with 220 nm diameter. In addition, the Au-MSNT clearly revealed the Au nanoparticles, with 9.3 ± 2.0 nm diameter. The Au-MSNT carried out the binding ability for protein as a guest molecule. The Au-MSNT acted as a receptor for the selective molecular recognition of biomolecules, particularly proteins containing cysteine. On the other hand, ubiquitin, which has no cysteine groups, was not immobilized onto the Au-MSNT. These results indicate that the Au-MSNT is efficiently recognized by the cysteine-containing protein. © 2008 American Chemical Society.
- DOI
- 10.1021/cm703674d
- Appears in Collections:
- 자연과학대학 > 생명과학전공 > Journal papers
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