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Au-droped magnetic silica nanotube for binding of cysteine-containing proteins

Title
Au-droped magnetic silica nanotube for binding of cysteine-containing proteins
Authors
Bae D.R.Lee S.J.Han S.W.Lim J.M.Kang D.Jung J.H.
Ewha Authors
강동민
SCOPUS Author ID
강동민scopus
Issue Date
2008
Journal Title
Chemistry of Materials
ISSN
0897-4756JCR Link
Citation
vol. 20, no. 12, pp. 3809 - 3813
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
The Au-doped magnetic silica nanotube (Au-MSNT) was fabricated by sol-gel transcription and its binding ability for proteins was carried out by TEM, FIF-IR, and confocal microscope. The nickel nanoparticles with 3.5 ± 1.0 nm are homogeneously deposited on the inner side of a silica nanotube (SNT) with 220 nm diameter. In addition, the Au-MSNT clearly revealed the Au nanoparticles, with 9.3 ± 2.0 nm diameter. The Au-MSNT carried out the binding ability for protein as a guest molecule. The Au-MSNT acted as a receptor for the selective molecular recognition of biomolecules, particularly proteins containing cysteine. On the other hand, ubiquitin, which has no cysteine groups, was not immobilized onto the Au-MSNT. These results indicate that the Au-MSNT is efficiently recognized by the cysteine-containing protein. © 2008 American Chemical Society.
DOI
10.1021/cm703674d
Appears in Collections:
자연과학대학 > 생명과학전공 > Journal papers
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