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Resting heart rate and aortic stiffness in normotensive adults

Title
Resting heart rate and aortic stiffness in normotensive adults
Authors
Logan J.G.Kim S.-S.
Ewha Authors
김석선
SCOPUS Author ID
김석선scopus
Issue Date
2016
Journal Title
Korean Circulation Journal
ISSN
1738-5520JCR Link
Citation
vol. 46, no. 6, pp. 834 - 840
Keywords
Arterial stiffnessCardiovascular diseasesHeart rateHypertensionPulse wave velocity
Publisher
Korean Society of Circulation
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
Background and Objective: Large-artery stiffness is an independent predictor of cardiovascular disease (CVD), and carotid-femoral pulse wave velocity (cfPWV) is considered the gold standard measure of arterial stiffness. A resting heart rate is an easily measured vital sign that is also associated with CVD morbidity and mortality. Previous studies have reported the significant relationship of a resting heart rate with arterial stiffness as measured by cfPWV only in hypertensive subjects; their relationship in nonhypertensive subjects remains unknown. The present study, therefore, examined their relationship in normotensive subjects. Subjects and Methods: In 102 healthy Korean Americans between ages 20 and 60 years, their resting heart rate was measured by an automated blood pressure measuring device after a 10 minute rest in the supine position. Arterial stiffness was measured by cfPWV using the SphygmoCor device. Results: The mean resting heart rate of participants (mean age, 39.64 years; 59% women) was 61.91 bpm (standard deviation [SD], 9.62 bpm) and mean the cfPWV was 6.99 (SD, 1.14) m/s. A multiple regression analysis showed that a resting heart rate is a significant predictor of cfPWV after controlling for age, body mass index, and mean arterial pressure. For one bpm increase of resting heart rate, cfPWV increased approximately 0.02 m/s. Conclusion: Our results suggest that a higher resting heart rate is independently associated with increased arterial stiffness as measured by cfPWV in normotensive adults. Arterial stiffness may explain the prognostic role of an individual's heart rate in cardiovascular morbidity and mortality. Copyright © 2016 The Korean Society of Cardiology.
DOI
10.4070/kcj.2016.46.6.834
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간호대학 > 간호학전공 > Journal papers
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