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Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange

Title
Chromofluorescent indicator for intracellular Zn2+/Hg 2+ dynamic exchange
Authors
Lee J.W.Jung H.S.Kwon P.S.Kim J.W.Bartsch R.A.Kim Y.Kim S.-J.Kim J.S.
Ewha Authors
김성진김영미
SCOPUS Author ID
김성진scopus; 김영미scopus
Issue Date
2008
Journal Title
Organic Letters
ISSN
1523-7060JCR Link
Citation
vol. 10, no. 17, pp. 3801 - 3804
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
(Chemical Equation Presented) (Figure Presented) The fluorescence of NABQ increases remarkably in the presence of Zn2+ and is quenched by Hg2+. As shown by confocal imaging, NABQ-Zn2+ can penetrate cells, where the bound Zn2+ is exchanged for Hg 2+. This results in the concomitant export of Hg2+ from the cells, showing that NABQ can act as a Zn2+ carrier and as a Hg2+ extracting agent in living cells. © 2008 American Chemical Society.
DOI
10.1021/ol801482n
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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