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Hydrogen peroxide induces hyphal differentiation in Candida albicans

Title
Hydrogen peroxide induces hyphal differentiation in Candida albicans
Authors
Nasution O.Srinivasa K.Kim M.Kim Y.-J.Kim W.Jeong W.Choi W.
Ewha Authors
최원자정우진
SCOPUS Author ID
최원자scopus; 정우진scopus
Issue Date
2008
Journal Title
Eukaryotic Cell
ISSN
1535-9778JCR Link
Citation
vol. 7, no. 11, pp. 2008 - 2011
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
In this study, we demonstrate that hyphal differentiation is induced by the subtoxic concentration of exogenous H2O2 in Candida albicans. This finding is confirmed by the changing intracellular concentration of H2O2. In order to induce the same level of differentiation, low concentrations of exogenous H2O2 are required for the null mutants of the thiol-specific antioxidant and catalase, while higher concentrations are needed for cells treated with ascorbic acid, an antioxidant chemical. Copyright © 2008, American Society for Microbiology. All Rights Reserved.
DOI
10.1128/EC.00105-08
Appears in Collections:
자연과학대학 > 생명과학전공 > Journal papers
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