DSpace at EWHA: Synthesis and antitumor activity of 1-beta-4-selenoarabinofuranosyl cytosine (4'-seleno-ara-C).

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DC Field	Value	Language
dc.contributor.author	정낙신	-
dc.contributor.author	이상국	-
dc.contributor.author	최원준	-
dc.date.accessioned	2016-11-25T02:11:29Z	-
dc.date.available	2016-11-25T02:11:29Z	-
dc.date.issued	2008	-
dc.identifier.issn	1746-8272	-
dc.identifier.other	OAK-18113	-
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/232816	-
dc.description.abstract	4-Seleno analogue of 1-beta-arabinofuranosyl cytosine (ara-C) was synthesized via 4'-selenouridine as a key intermediate, which was easily prepared from D-ribose. The arabino configuration was achieved by chemoselective ring opening of the 2,2'-anhydro-4'-selenouridine. The synthesized 4'-seleno-ara-C showed potent antitumor activity (IC(50) = 1.5 microM) against stomach cancer cells (SNU638).	-
dc.language	English	-
dc.title	Synthesis and antitumor activity of 1-beta-4-selenoarabinofuranosyl cytosine (4'-seleno-ara-C).	-
dc.type	Article	-
dc.relation.issue	52	-
dc.relation.index	SCOPUS	-
dc.relation.startpage	639	-
dc.relation.lastpage	640	-
dc.relation.journaltitle	Nucleic acids symposium series (2004)	-
dc.identifier.scopusid	2-s2.0-78649436192	-
dc.author.google	Lee H.	-
dc.author.google	Tosh D.K.	-
dc.author.google	Choi W.J.	-
dc.author.google	Kim Y.M.	-
dc.author.google	Lee S.K.	-
dc.author.google	Jeong L.S.	-
dc.contributor.scopusid	정낙신(16028528200)	-
dc.contributor.scopusid	이상국(36067620500)	-
dc.contributor.scopusid	최원준(55732412300;57211762651)	-
dc.date.modifydate	20230627112239	-