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Boronate based fluorescence (ESIPT) probe for peroxynitrite
- Title
- Boronate based fluorescence (ESIPT) probe for peroxynitrite
- Authors
- Sedgwick, Adam C.; Sun, Xiaolong; Kim, Gyoungmi; Yoon, Juyoung; Bull, Steven D.; James, Tony D.
- Ewha Authors
- 윤주영
- SCOPUS Author ID
- 윤주영
- Issue Date
- 2016
- Journal Title
- CHEMICAL COMMUNICATIONS
- ISSN
- 1359-7345
1364-548X
- Citation
- CHEMICAL COMMUNICATIONS vol. 52, no. 83, pp. 12350 - 12352
- Publisher
- ROYAL SOC CHEMISTRY
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester "protecting'' unit. The "protecting'' unit of the probe is removed by peroxynitrite to "turn-on'' ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off-on response towards peroxynitrite, in HeLa and RAW 264.7 cells.
- DOI
- 10.1039/c6cc06829d
- Appears in Collections:
- 자연과학대학 > 화학·나노과학전공 > Journal papers
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