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Boronate based fluorescence (ESIPT) probe for peroxynitrite

Title
Boronate based fluorescence (ESIPT) probe for peroxynitrite
Authors
Sedgwick, Adam C.Sun, XiaolongKim, GyoungmiYoon, JuyoungBull, Steven D.James, Tony D.
Ewha Authors
윤주영
SCOPUS Author ID
윤주영scopus
Issue Date
2016
Journal Title
CHEMICAL COMMUNICATIONS
ISSN
1359-7345JCR Link1364-548XJCR Link
Citation
vol. 52, no. 83, pp. 12350 - 12352
Publisher
ROYAL SOC CHEMISTRY
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester "protecting'' unit. The "protecting'' unit of the probe is removed by peroxynitrite to "turn-on'' ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off-on response towards peroxynitrite, in HeLa and RAW 264.7 cells.
DOI
10.1039/c6cc06829d
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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