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An NBD-based colorimetric and fluorescent chemosensor for Zn2+ and its use for detection of intracellular zinc ions

Title
An NBD-based colorimetric and fluorescent chemosensor for Zn2+ and its use for detection of intracellular zinc ions
Authors
Xu Z.Kim G.-H.Han S.J.Jou M.J.Lee C.Shin I.Yoon J.
Ewha Authors
이종목윤주영
SCOPUS Author ID
이종목scopus; 윤주영scopus
Issue Date
2009
Journal Title
Tetrahedron
ISSN
0040-4020JCR Link
Citation
vol. 65, no. 11, pp. 2307 - 2312
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
A new 7-nitrobenz-2-oxa-1,3-diazole (NBD) based colorimetric and fluorescence chemosensor for Zn2+, an ion involved in many biological processes, was designed and synthesized. The NBD-probe 1 displays a red-to-yellow color change and an enhancement of fluorescent intensity in the presence of an aqueous solution of Zn2+ ions (pH 7.2). Internal charge transfer (ICT) and photoinduced electron transfer (PET) mechanisms are responsible for these changes. The practical use of this probe was demonstrated by its application to the biologically relevant detection of Zn2+ ions in pancreatic β-cells. © 2009 Elsevier Ltd. All rights reserved.
DOI
10.1016/j.tet.2009.01.035
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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