Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정병문 | * |
dc.contributor.author | 김진흥 | * |
dc.date.accessioned | 2016-08-29T11:08:34Z | - |
dc.date.available | 2016-08-29T11:08:34Z | - |
dc.date.issued | 2009 | * |
dc.identifier.issn | 0920-5063 | * |
dc.identifier.other | OAK-5666 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/231947 | - |
dc.description.abstract | We report here that the incorporation of several disulfide bonds along poly(ethylene glycol) (PEG) gives temperature sensitivity, as well as biodegradability to PEG. To synthesize a PEG with temperature sensitivity in a physiologically important range (20-40°C), PEGs with molecular masses of 400 and 600 Da were randomly coupled by disulfide bonds. As the mol ratio of PEG (400 Da) disulfide to PEG (600 Da) disulfide increased from 40:60 to 60:40, the cloud point of the polymer aqueous solution decreased from 35°C to 27°C. The disulfide bonds between PEGs were degraded in the presence of a thiol-containing biomolecule of glutathione in a thiol-concentration-dependent manner. © 2009 Koninklijke Brill NV, Leiden. | * |
dc.language | English | * |
dc.title | Temperature-sensitive biodegradable poly(ethylene glycol) | * |
dc.type | Article | * |
dc.relation.issue | 41463 | * |
dc.relation.volume | 20 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 957 | * |
dc.relation.lastpage | 965 | * |
dc.relation.journaltitle | Journal of Biomaterials Science, Polymer Edition | * |
dc.identifier.doi | 10.1163/156856209X444367 | * |
dc.identifier.wosid | WOS:000266662600006 | * |
dc.identifier.scopusid | 2-s2.0-67649112548 | * |
dc.author.google | Lee J. | * |
dc.author.google | Joo M.K. | * |
dc.author.google | Kim J. | * |
dc.author.google | Park J.S. | * |
dc.author.google | Yoon M.-Y. | * |
dc.author.google | Jeong B. | * |
dc.contributor.scopusid | 정병문(7102237959) | * |
dc.contributor.scopusid | 김진흥(8580015800) | * |
dc.date.modifydate | 20240118155902 | * |