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Phenotypic plasticity promotes balanced polymorphism in periodic environments by a genomic storage effect

Title
Phenotypic plasticity promotes balanced polymorphism in periodic environments by a genomic storage effect
Authors
Gulisija D.Kim Y.Plotkin J.B.
Ewha Authors
김유섭
SCOPUS Author ID
김유섭scopus
Issue Date
2016
Journal Title
Genetics
ISSN
0016-6731JCR Link
Citation
vol. 202, no. 4, pp. 1437 - 1448
Keywords
Balanced polymorphismPhenotypic plasticityStorage effectTemporally varying selection
Publisher
Genetics
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Phenotypic plasticity is known to evolve in perturbed habitats, where it alleviates the deleterious effects of selection. But the effects of plasticity on levels of genetic polymorphism, an important precursor to adaptation in temporally varying environments, are unclear. Here we develop a haploid, two-locus population-genetic model to describe the interplay between a plasticity modifier locus and a target locus subject to periodically varying selection. We find that the interplay between these two loci can produce a “genomic storage effect” that promotes balanced polymorphism over a large range of parameters, in the absence of all other conditions known to maintain genetic variation. The genomic storage effect arises as recombination allows alleles at the two loci to escape more harmful genetic backgrounds and associate in haplotypes that persist until environmental conditions change. Using both Monte Carlo simulations and analytical approximations we quantify the strength of the genomic storage effect across a range of selection pressures, recombination rates, plasticity modifier effect sizes, and environmental periods. © 2016 by the Genetics Society of America.
DOI
10.1534/genetics.115.185702
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자연과학대학 > 생명과학전공 > Journal papers
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