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The comparison of constituents distributed in the root of Angelica dahurica

Title
The comparison of constituents distributed in the root of Angelica dahurica
Authors
Youn U.J.Yoo J.K.Chen Q.G.Lee I.S.Na M.Min B.-S.Jung H.-J.Seo E.-K.Bae K.
Ewha Authors
서은경
SCOPUS Author ID
서은경scopus
Issue Date
2010
Journal Title
Korean Journal of Pharmacognosy
ISSN
0253-3073JCR Link
Citation
vol. 41, no. 3, pp. 185 - 189
Indexed
SCOPUS; KCI scopus
Abstract
In this study, we analyzed and quantified the amounts of bioactive phenolic constituents, xanthotoxin (1), oxypeucedanin (2), and imperatorin (3) in each part of the root of Angelica dahurica by HPLC, which validated by ICH guide lines comparing the linearity, intra day precision, inter-day precision. As a result, the amount of imperatorin 2.96% in the rootlet was two fold higher than that of the main root 1.32%. On the other hand, the amounts of xanthotoxin and oxypeucedanin in the rootlet showed similar to those of main root. In addition, the cortex of root is more plentiful of three consitituents (0.66%, 0.53%, and 1.85%) than those of xylem (0.29%, 0.05%, and 0.07%). These results show that the rootlet and cortex contain a large amount of bioactive phenolic constituent including xanthotoxin, oxypeucedanin, and imperatorin than other parts of the root.
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약학대학 > 약학과 > Journal papers
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