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자연과학대학
화학·나노과학전공
Journal papers
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Two new Scalaranes from a Korean marine sponge Spongia sp
Title
Two new Scalaranes from a Korean marine sponge Spongia sp
Authors
Yang I.
;
Nam S.-J.
;
Kang H.
Ewha Authors
남상집
SCOPUS Author ID
남상집
Issue Date
2015
Journal Title
Natural Product Sciences
ISSN
1226-3907
Citation
Natural Product Sciences vol. 21, no. 4, pp. 289 - 292
Keywords
Korean sponge
;
Marine natural product
;
Scalarane
;
Sesterpenoid
;
Spongia sp
Publisher
Korean Society of Pharmacognosy
Indexed
SCOPUS; KCI
Document Type
Article
Abstract
Intensive chemical investigation of Korean marine sponge Spongia sp. has led to the isolation of two new scalaranes. The planar structures of the new compounds 1 and 2 were determined through 1D and 2D NMR spectral data analysis, while the relative stereochemistry of the compounds was determined based on the analysis of 1H-1H coupling constants and NOESY spectroscopic data. Compounds 1 and 2 did not display any significant biological activities on farnesoid X-activated receptor (FXR) in co-transfection assay. © 2015, Korean Society of Pharmacognosy. All rights reserved.
DOI
10.20307/nps.2015.21.4.289
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