Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박준우 | - |
dc.date.accessioned | 2016-08-28T11:08:05Z | - |
dc.date.available | 2016-08-28T11:08:05Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0021-9258 | - |
dc.identifier.other | OAK-13940 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/229881 | - |
dc.description.abstract | Background: Ceramide synthase 2 null mice, which cannot synthesize very-long chain ceramides, display severe hepatopathy. Results: These mice have elevated sphinganine and altered N-acyl chain ceramides that disrupt mitochondrial function by modifying respiratory chain activity. Conclusion: Alteration of mitochondrial sphingolipids results in formation of reaction oxygen species in liver. Significance: Ceramides with defined acyl chains influence oxidative stress signaling pathways.© 2013 by The American Society for Biochemistry and Molecular Biology, Inc. | - |
dc.language | English | - |
dc.title | Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain | - |
dc.type | Article | - |
dc.relation.issue | 7 | - |
dc.relation.volume | 288 | - |
dc.relation.index | SCI | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 4947 | - |
dc.relation.lastpage | 4956 | - |
dc.relation.journaltitle | Journal of Biological Chemistry | - |
dc.identifier.doi | 10.1074/jbc.M112.402719 | - |
dc.identifier.scopusid | 2-s2.0-84874086182 | - |
dc.author.google | Zigdon H. | - |
dc.author.google | Kogot-Levin A. | - |
dc.author.google | Park J.-W. | - |
dc.author.google | Goldschmidt R. | - |
dc.author.google | Kelly S. | - |
dc.author.google | Merrill Jr. A.H. | - |
dc.author.google | Scherz A. | - |
dc.author.google | Pewzner-Jung Y. | - |
dc.author.google | Saada A. | - |
dc.author.google | Futerman A.H. | - |
dc.contributor.scopusid | 박준우(35332923800) | - |
dc.date.modifydate | 20220119160750 | - |