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공과대학
전자전기공학전공
Journal papers
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In vivo optical neural recording using fiber-based surface plasmon resonance
Title
In vivo optical neural recording using fiber-based surface plasmon resonance
Authors
Kim S.A.
;
Kim S.J.
;
Moon H.
;
Jun S.B.
Ewha Authors
전상범
SCOPUS Author ID
전상범
Issue Date
2012
Journal Title
Optics Letters
ISSN
0146-9592
Citation
Optics Letters vol. 37, no. 4, pp. 614 - 616
Indexed
SCI; SCIE; SCOPUS
Document Type
Article
Abstract
We propose an intrinsic optical method for in vivo neural recording using optic fiber-based surface plasmon resonance (SPR) phenomena. The fiber-based SPR method is electrical artifact free, labeling free, and feasible for a portable system compared with conventional in vivo neural recording systems. We simultaneously detected SPR signals and electrical neural activity from the rat somatosensory cortex evoked by electrical stimulation on the forepaw. Pharmacological analysis using a voltage-gated sodium channel blocker confirmed the neural origins of the optical signals. This fiber-based SPR system promises the enhanced ability to record in vivo neural activity for the investigation of neurons and their networks. © 2012 Optical Society of America.
DOI
10.1364/OL.37.000614
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