View : 24 Download: 3

Primo Vascular System of Murine Melanoma and Heterogeneity of Tissue Oxygenation of the Melanoma

Title
Primo Vascular System of Murine Melanoma and Heterogeneity of Tissue Oxygenation of the Melanoma
Authors
Hong M.Park S.S.Do H.Jhon G.-J.Suh M.Lee Y.
Ewha Authors
전길자이영미
SCOPUS Author ID
전길자scopus; 이영미scopus
Issue Date
2011
Journal Title
JAMS Journal of Acupuncture and Meridian Studies
ISSN
2005-2901JCR Link
Citation
vol. 4, no. 3, pp. 159 - 163
Indexed
SCOPUS; KCI scopus
Abstract
Murine melanoma requires the complex development of lymphatic, vascular, and non-vascular structures. A possible relationship between the primo vascular system (PVS) and the melanoma metastasis has been proposed. In particular, the PVS may be involved in oxygen transport. Vasculogenic-like networks, similar to the PVS, have been found within melanoma tumors, but their functional relationship with the PVS and meridian structures are unclear. Herein, we report on the use of an electrochemical O 2 sensor to study oxygenation levels of melanoma tumors in mice. We consistently found higher tissue oxygenation in specific sites of tumors (n=5). These sites were strongly associated with vascular structures or the PVS. Furthermore, the PVS on the tumor surface was associated with adipose tissue. Our findings suggest that the PVS is involved in the regulation of metastasis. © 2011.
DOI
10.1016/j.jams.2011.09.002
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
Files in This Item:
001.pdf(976.23 kB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE