Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서은경 | * |
dc.date.accessioned | 2016-08-28T11:08:19Z | - |
dc.date.available | 2016-08-28T11:08:19Z | - |
dc.date.issued | 2010 | * |
dc.identifier.issn | 1612-1872 | * |
dc.identifier.other | OAK-13469 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/229461 | - |
dc.description.abstract | Four known alkyl 4-hydroxybenzoates, i.e., methyl 4-hydroxybenzoate (1), ethyl 4-hydroxybenzoate (2), propyl 4-hydroxybenzoate (3), and butyl 4-hydroxybenzoate (4), were isolated from the seeds of Nelumbo nucifera GAERTNER (Nymphaeaceae) for the first time. The structures of the isolates were identified by 1D- and 2D-NMR spectroscopy and comparison with published values. The compounds were evaluated for their effects on the 5-HT-stimulated inward current (I5-HT) mediated by the human 5-HT3A receptors expressed in Xenopus oocytes. Compounds 1 and 2 enhanced the I5-HT, but 4 reduced it. These results indicate that 4 is an inhibitor of the 5-HT 3A receptors expressed in Xenopus oocytes. © 2010 Verlag Helvetica Chimica Acta AG. | * |
dc.language | English | * |
dc.title | Regulation of the 5-HT3A receptor-mediated current by alkyl 4-hydroxybenzoates isolated from the seeds of Nelumbo nucifera | * |
dc.type | Article | * |
dc.relation.issue | 9 | * |
dc.relation.volume | 7 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 2296 | * |
dc.relation.lastpage | 2302 | * |
dc.relation.journaltitle | Chemistry and Biodiversity | * |
dc.identifier.doi | 10.1002/cbdv.200900393 | * |
dc.identifier.wosid | WOS:000288457500011 | * |
dc.identifier.scopusid | 2-s2.0-77956944776 | * |
dc.author.google | Youn U.J. | * |
dc.author.google | Lee J.-H. | * |
dc.author.google | Lee Y.J. | * |
dc.author.google | Nam J.W. | * |
dc.author.google | Bae H. | * |
dc.author.google | Seo E.-K. | * |
dc.contributor.scopusid | 서은경(7005953758) | * |
dc.date.modifydate | 20240118144717 | * |