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Clinical spectrum of reflux esophagitis among 25,536 Koreans who underwent a health check-up: A nationwide multicenter prospective, endoscopy-based Study

Title
Clinical spectrum of reflux esophagitis among 25,536 Koreans who underwent a health check-up: A nationwide multicenter prospective, endoscopy-based Study
Authors
Shim K.-N.Hong S.J.Sung J.K.Park K.S.Kim S.-E.Park H.-S.Kim Y.S.Lim S.H.Kim C.H.Park M.J.Yim J.Y.Cho K.R.Kim D.Park S.J.Jee S.-R.Kim J.I.Park J.Y.Song G.A.Jung H.-Y.Lee Y.C.Kim J.G.Kim J.J.Kim N.Park S.-H.Jung H.C.Chung I.-S.
Ewha Authors
심기남김성은
SCOPUS Author ID
심기남scopus; 김성은scopus
Issue Date
2009
Journal Title
Journal of Clinical Gastroenterology
ISSN
0192-0790JCR Link
Citation
vol. 43, no. 7, pp. 632 - 638
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Background: Gastroesophageal reflux is a commonly encountered condition, but detailed data on reflux symptoms in Asian countries are lacking. Goals: To evaluate the prevalence and to document the clinical spectrum of endoscopic reflux esophagitis (RE). Study: A total 25,536 subjects underwent an upper gastrointestinal endoscopic examination as part of a health check, and completed a gastroesophageal reflux questionnaire. Endoscopic findings classified according to the Los Angeles (LA) classification and the data from gastroesophageal reflux questionnaire were analyzed. Results: On the basis of endoscopic findings, 2019 subjects (7.91%) were found to have RE: 5.87% in LA-A; 1.84% in LA-B; 0.18% in LA-C; and 0.02% in LA-D. Heartburn, acid regurgitation, chest pain, hoarseness, globus sensation, cough, and epigastric soreness were found to be associated with RE (P<0.05). Heartburn, acid regurgitation, and epigastric soreness were more frequent in LA-B than in LA-A (P<0.05). Epigastric soreness was most bothersome in LA-A and LA-B, and acid regurgitation was most bothersome in LA-C and LA-D (P<0.01). Heartburn, hoarseness, and globus sensation were more frequent in men with RE, and acid regurgitation was most common in women. Conclusions: The prevalence of RE was found to be 7.91% in Korea, and the profiles of reflux symptoms were found to depend on grade of RE and sex. © 2009 Lippincott Williams & Wilkins, Inc.
DOI
10.1097/MCG.0b013e3181855055
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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