Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서은경 | * |
dc.date.accessioned | 2016-08-28T11:08:56Z | - |
dc.date.available | 2016-08-28T11:08:56Z | - |
dc.date.issued | 2009 | * |
dc.identifier.issn | 0009-2363 | * |
dc.identifier.other | OAK-13196 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/229226 | - |
dc.description.abstract | A new stereoisomer of 8-O-4′ system neolignan, (7R,8S)-1-(3,4- dimethoxyphenyl)-2-[4-(3-hydroxy-1-propenyl)-2-methoxyphenoxy]-propane-1,3-diol (1) and a new stereoisomer of tetrahydrofuranoid lignan, (7R,8S,7'S,8'R)-(3,4,5, 3′,4′)-pentamethoxy-9,7′-dihydroxy-8.8′,7.0. 9′-lignan (2) along with seven known lignans and neolignans (3-9) were isolated from the methanol extracts of the flower buds of Magnolia fargesii. The structures of these compounds (1-9) were elucidated by spectroscopic methods including 1D- and 2D-NMR as well as by comparison with reported values. Absolute configurations of new stereoisomers 1 and 2 were determined by circular dichroism (CD) spectra. The absolute configuration of (S,8S,10S)-[tetrahydro-4- hydroxy-2-(3,4,5-tri-methoxyphenyl)furan-3-yl]methyl 3,4-dimethoxy benzoate (3) was determined by Mosher's esterification method for the first time in this study. Three lignans, tanegool (4), (+)-dehydrodiconiferyl alcohol (5), and epieudes-min (6), were isolated from this plant for the first time. Superoxide radical scavenging activities of the isolates (1-9) were measured by irradiated riboflavin/ethylenediaminetetraacetic acid (EDTA)/Nitroblue tetrazolium (NBT) system, and their in vitro rat lens aldose reductase (RLAR) inhibitory activities were also evaluated. © 2009 Pharmaceutical Society of Japan. | * |
dc.language | English | * |
dc.title | Two new stereoisomers of neolignan and lignan from the flower buds of magnolia fargesii | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 57 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 298 | * |
dc.relation.lastpage | 301 | * |
dc.relation.journaltitle | Chemical and Pharmaceutical Bulletin | * |
dc.identifier.doi | 10.1248/cpb.57.298 | * |
dc.identifier.wosid | WOS:000263779500014 | * |
dc.identifier.scopusid | 2-s2.0-62549091473 | * |
dc.author.google | Lee J. | * |
dc.author.google | Seo E.-K. | * |
dc.author.google | Jang D.S. | * |
dc.author.google | Ha T.J. | * |
dc.author.google | Jong-Pyung K.I.M. | * |
dc.author.google | Nam J.-W. | * |
dc.author.google | Bae G. | * |
dc.author.google | Lee Y.M. | * |
dc.author.google | Yang M.S. | * |
dc.author.google | Kim J.S. | * |
dc.contributor.scopusid | 서은경(7005953758) | * |
dc.date.modifydate | 20240118144717 | * |