Synthesis of benzo[b]naphtho[2,3-d]thiophene-6,11-diones via palladium(II) acetate-mediated cyclization of 3-arylthio-1,4-naphthoquinone

Abstract

Palladium(II)-mediated oxidative cyclization of 3-arylthio-1,4- naphthoquinone (4) giving biologically important benzo[b]naphtho-[2,3-d] thiophene-6,11-diones (2) has been performed with a stoichiometric amount of palladium(II) acetate in distillated acetic acid.