Poly(L-lactide) membranes with biomimetic nanolayer for efficient bone induction for tissue regenerative therapy

Abstract

The use of nanoparticles of collagen, gelatin, and chitosan modified poly(L-lactide (PLLA) membranes for efficient bone induction in tissue regenerative therapy was analyzed. For the study, PLLA was dissolved in 6mL of methylene chloride mixed with 3mL of ethyl acetate and the morphology of membranes was examined by using a scanning electron microscope (SEM). It was observed that the nanofibers made of the dissolution of the collagen and gelatin are attached to the membrane. It was suggested that PLLA membranes made by electrospinning methods for surface modification can improve the biological properties of the membranes.