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Biomimetic micro-and nanofibrous scaffold for enhanced cartilage regeneration

Title
Biomimetic micro-and nanofibrous scaffold for enhanced cartilage regeneration
Authors
Shim I.K.Hwang J.H.Ahn H.J.Lee S.H.Lee M.C.Lee S.J.
Ewha Authors
이승진심인경
SCOPUS Author ID
이승진scopus
Issue Date
2004
Journal Title
Transactions - 7th World Biomaterials Congress
Indexed
SCOPUS scopus
Abstract
Biomimetic three-dimensional (3-D) micro-and nanofibrous scaffolds based on collagen nanofibers for chondrocyte culture and cartilage regeneration were investigated. PLGA solution and chitosan solution were homogenized using tween 80 as a emulsifier. PLGA/chitosan microfiber was fabricated by extruding the solution mixture into alkali methanol solution using 0.02mm nozzles. The morphology of fibrous matrices was examined by using a scanning electron microscope (SEM). Results show that micro-and nanofibrous matrix chondrocytes maintained spherical morphology and formed dense layer of cartilaginous tissue.
ISBN
1877040193; 9781877040191
Appears in Collections:
약학대학 > 약학과 > Journal papers
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