DSpace at EWHA: Cytotoxic effects of quinoxaline derivatives on human cancer cell lines

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DC Field	Value	Language
dc.contributor.author	서명은	*
dc.date.accessioned	2016-08-28T11:08:35Z	-
dc.date.available	2016-08-28T11:08:35Z	-
dc.date.issued	1998	*
dc.identifier.issn	0365-6233	*
dc.identifier.other	OAK-12522	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/228651	-
dc.description.abstract	The cytotoxicities of 6,7-modified-5,8-quinoxalinedione derivatives and heterocyclic quinoxaline derivatives containing nitrogen, sulfur, and oxygen on human lung adenocarcinoma cell (PC 14), human gastric adenocarcinoma cell (MKN 45), and human colon adenocarcinoma cell (colon 205) were examined in vitro using MTT assay. Pyrido[1,2-a]imidazo[4,5-g]quinoxaline-6,11-dione (10) was markedly cytotoxic against MKN 45 compared with adriamycin and cis- platin used as anticancer drugs. The IC50 value of compound 10 was 0.073 μM while those of adriamycin and cis-platin were 0.12 μM and 2.67 μM, respectively.	*
dc.language	English	*
dc.title	Cytotoxic effects of quinoxaline derivatives on human cancer cell lines	*
dc.type	Article	*
dc.relation.issue	10	*
dc.relation.volume	331	*
dc.relation.index	SCI	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	331	*
dc.relation.lastpage	333	*
dc.relation.journaltitle	Archiv der Pharmazie	*
dc.identifier.doi	10.1002/(SICI)1521-4184(199810)331:10&lt	*
dc.identifier.doi	331::AID-ARDP331&gt	*
dc.identifier.doi	3.0.CO	*
dc.identifier.doi	2-I	*
dc.identifier.wosid	WOS:000077014100006	*
dc.identifier.scopusid	2-s2.0-0031726936	*
dc.author.google	Yoo H.-W.	*
dc.author.google	Lee Y.-S.	*
dc.author.google	Suh M.E.	*
dc.author.google	Kim D.J.	*
dc.author.google	Park S.W.	*
dc.contributor.scopusid	서명은(7103253844)	*
dc.date.modifydate	20240423081003	*