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Acyl-CoA : Cholesterol acyltransferase inhibitors from Magnolia obovata

Title
Acyl-CoA : Cholesterol acyltransferase inhibitors from Magnolia obovata
Authors
Kwon B.-M.Kim M.-K.Lee S.-H.Kim J.-A.Lee I.-R.Kim Y.-K.Bok S.-H.
Ewha Authors
이인란
SCOPUS Author ID
이인란scopusscopus
Issue Date
1997
Journal Title
Planta Medica
ISSN
0032-0943JCR Link
Citation
vol. 63, no. 6, pp. 550 - 551
Indexed
SCI; SCIE; SCOPUS scopus
Abstract
In the course of a search for acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors from natural sources, new types of ACAT inhibitors were isolated from the extract of Magnolia obovata leaves, and identified as obovatol, honokiol, and magnolol. The active compounds inhibit rat liver ACAT with IC50 values of 42, 71, and 86 μM, respectively.
DOI
10.1055/s-2006-957762
Appears in Collections:
약학대학 > 약학과 > Journal papers
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