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Rhombenone: Farnesyl protein transferase inhibitor from the leaves of Hedera rhombea Bean

Title
Rhombenone: Farnesyl protein transferase inhibitor from the leaves of Hedera rhombea Bean
Authors
Kwon B.-M.Lee S.-H.Kim K.-S.Lee I.-R.Lee U.C.Hong S.-H.Bok S.-H.
Ewha Authors
이인란
SCOPUS Author ID
이인란scopusscopus
Issue Date
1997
Journal Title
Bioorganic and Medicinal Chemistry Letters
ISSN
0960-894XJCR Link
Citation
vol. 7, no. 8, pp. 971 - 974
Indexed
SCI; SCIE; SCOPUS scopus
Abstract
Rhombenone, a new dammarane analogue containing an 25-oxo, which inhibits farnesyl protein transferase (FPTase), was isolated from the leaves of Hedera rhombea Bean. Additional related dammaranes were also evaluated for FPTase inhibition.
DOI
10.1016/S0960-894X(97)00139-X
Appears in Collections:
약학대학 > 약학과 > Journal papers
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