View : 40 Download: 0

The antimicrobial activities of some 1,4-naphthalenediones (IV)

Title
The antimicrobial activities of some 1,4-naphthalenediones (IV)
Authors
Ryu C.-K.Kim D.-H.Kim H.-J.Chung S.-Y.
Ewha Authors
유충규김희정
SCOPUS Author ID
유충규scopus; 김희정scopusscopusscopus
Issue Date
1993
Journal Title
Archives of Pharmacal Research
ISSN
0253-6269JCR Link
Citation
vol. 16, no. 4, pp. 327 - 330
Indexed
SCIE; SCOPUS; KCI scopus
Abstract
A series of 2-chloro and 2-bromo-3-(substituted)-1,4-naphthalenedione derivatives (1-25) were tested for antifungal and antibacterial activities in vitro against Candida albicans 10231 and Local, Aspergillus niger KCTC 1231, Tricophyton mentagrophytes KCTC 6085, Fusarium oxysporium KTCC 6051, Bacillus subtilis ATCC 6633, Pseudomonas aeruginosa NCTC 10490, Staphylococcus aureus ATCC 6538p, Escherichia coli NIHJ and Acinetobacter baumanii Local. The MIC values were determined by the twofold agar dilution/streak method. Among these derivatives, 1, 9, 20, 21, 23 and 25 showed more potent antifungal activities than fluconazole. 20 and 23 completely inhibited the growth of fungi, such as Candida albicans, Aspergillus niger, Tricophyton mentagrophytes and Fusarium oxysporium, at 3.2 μg/ml. Also some derivatives had the antibacterial activities against Gram-positive bacteria. © 1993 The Pharmaceutical Society of Korea.
DOI
10.1007/BF02977525
Appears in Collections:
약학대학 > 약학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE