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Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors

Title
Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors
Authors
Karki R.Park C.Jun K.-Y.Jee J.-G.Lee J.-H.Thapa P.Kadayat T.M.Kwon Y.Lee E.-S.
Ewha Authors
권영주
SCOPUS Author ID
권영주scopus
Issue Date
2014
Journal Title
European Journal of Medicinal Chemistry
ISSN
1768-3254JCR Link
Citation
vol. 84, pp. 555 - 565
Publisher
Elsevier Masson SAS
Indexed
SCOPUS WOS scopus
Abstract
Anticancer agents; Cytotoxicity; Docking study; Topo II inhibitory activity; Topoisomerase I; Topoisomerase II; Trihydroxylated 2,4,6-triphenyl pyridines
DOI
10.1016/j.ejmech.2014.07.058
Appears in Collections:
약학대학 > 약학과 > Journal papers
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