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Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors

Title: Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors

Authors: Kim M.; Lee J.; Jung K.; Kim H.; Aman W.; Ryu J.-S.; Hah J.-M.

Ewha Authors: 류재상

SCOPUS Author ID: 류재상

Issue Date: 2014

Journal Title: Bioorganic and Medicinal Chemistry Letters

ISSN: 1464-3405

Citation: Bioorganic and Medicinal Chemistry Letters vol. 24, no. 15, pp. 3600 - 3604

Publisher: Elsevier Ltd

Indexed: SCI; SCIE; SCOPUS

Document Type: Article

Abstract: (4-Aminobenzyl)-1H-imidazol-1-yl pyrimidin-2-yl derivatives; Antiproliferative activity; BRAF V600E; CRAF; Melanoma; Selectivity

DOI: 10.1016/j.bmcl.2014.05.030

Appears in Collections:: 약학대학 > 약학과 > Journal papers

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