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Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor

Title: Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor

Authors: Jun K.-Y.; Kwon H.; Park S.-E.; Lee E.; Karki R.; Thapa P.; Lee J.-H.; Lee E.-S.; Kwon Y.

Ewha Authors: 권영주

SCOPUS Author ID: 권영주

Issue Date: 2014

Journal Title: European Journal of Medicinal Chemistry

ISSN: 1768-3254

Citation: European Journal of Medicinal Chemistry vol. 80, pp. 428 - 438

Publisher: Elsevier Masson SAS

Indexed: SCOPUS

Document Type: Article

Abstract: 3D-QSAR; Anticancer agents; Cytotoxicity; Dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridines; Topoisomerase I; Topoisomerase II

DOI: 10.1016/j.ejmech.2014.04.066

Appears in Collections:: 약학대학 > 약학과 > Journal papers

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