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Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor

Title
Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor
Authors
Jun K.-Y.Kwon H.Park S.-E.Lee E.Karki R.Thapa P.Lee J.-H.Lee E.-S.Kwon Y.
Ewha Authors
권영주
SCOPUS Author ID
권영주scopus
Issue Date
2014
Journal Title
European Journal of Medicinal Chemistry
ISSN
1768-3254JCR Link
Citation
vol. 80, pp. 428 - 438
Publisher
Elsevier Masson SAS
Indexed
SCOPUS WOS scopus
Abstract
3D-QSAR; Anticancer agents; Cytotoxicity; Dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridines; Topoisomerase I; Topoisomerase II
DOI
10.1016/j.ejmech.2014.04.066
Appears in Collections:
약학대학 > 약학과 > Journal papers
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